2 (Dual)
GH Receptors
2–3×
Daily Injections
12–16 wks
Cycle Length
CJC-1295 / Ipamorelin
The Gold Standard GH Stack
Pre-blended GHRH + GHRP combo — the most synergistic growth hormone protocol. Dual-receptor stimulation produces GH pulses far beyond either peptide alone for lean mass and recovery.
Starting From
$50.00
Sold By
Apollo Peptide Sciences
Suggested Protocol
100mcg CJC-1295 + 100mcg Ipamorelin per injection (from blended vial), 2–3× daily. Best timed: upon waking, pre-workout, and 30–60 min before bed. The bedtime dose leverages the natural GH pulse during sleep. Cycles of 12–16 weeks on, 4–8 weeks off.
Why Two Receptors Produce More Than Twice the Growth Hormone of Either Alone
The CJC-1295 / Ipamorelin combination is widely regarded as the most effective and safest growth hormone optimization protocol available in peptide form. Apollo Peptide Sciences supplies this as a pre-blended 5mg/5mg vial, eliminating the need to source and combine two separate compounds.
The synergy is pharmacological: CJC-1295 is a GHRH (Growth Hormone Releasing Hormone) analogue that activates the GHRH receptor on pituitary somatotrophs, while Ipamorelin is a ghrelin-mimetic GHRP that activates the ghrelin receptor through a completely different pathway. When both receptors are stimulated simultaneously, the resulting GH pulse is substantially greater than either compound alone — a "double stimulus" that researchers have described as approaching pharmaceutical GH levels while remaining entirely within the body's own regulatory feedback mechanisms.
Critically, Ipamorelin provides this potent GH stimulation with extraordinary selectivity: unlike other GHRPs (GHRP-6, GHRP-2), it does not elevate cortisol, prolactin, or ACTH — ensuring the full benefit of GH elevation without hormonal interference. This selectivity is why Ipamorelin has become the standard GHRP component in premium GH protocols.
The downstream effects of optimized GH pulsatility are comprehensive: enhanced fat mobilization and lipolysis, improved lean muscle preservation and growth via IGF-1 elevation, dramatically improved deep sleep architecture, faster recovery from training, and improved skin thickness and elasticity as collateral benefits of increased IGF-1.
The Dual Receptor Advantage
GHRH + GHRP Simultaneously: The Synergy That Makes This Stack the Gold Standard
CJC-1295 activates the GHRH receptor on pituitary somatotrophs — the cells that produce growth hormone. Ipamorelin activates the ghrelin receptor (GHS-R) through an entirely separate pathway. When both receptors are stimulated simultaneously, the GH pulse isn't just additive — it's synergistic. Research has described this as a "double stimulus" effect: the combined receptor activation produces GH pulsatility that approaches pharmaceutical GH levels while remaining entirely within the body's own feedback mechanisms. Neither compound alone achieves what both achieve together — which is exactly why this stack became the standard.
Ipamorelin's Selectivity
Zero Cortisol. Zero Prolactin. Just Clean GH Elevation — Here's Why That Matters
Older GHRPs like GHRP-6 and GHRP-2 produce significant GH elevation but come with a cost: they also raise cortisol and prolactin. Cortisol is catabolic — it breaks down muscle, promotes fat storage, and undermines every result you're trying to achieve with a GH protocol. Ipamorelin's extraordinary selectivity means you get the full GH-stimulating benefit of GHRP activation with zero cortisol or prolactin response. This is the core reason Ipamorelin replaced other GHRPs as the standard in premium GH protocols — it's not just effective, it's clean.
The Bedtime Dose
Why the Last Injection of the Day Is the Most Important One You'll Take
Growth hormone release is highest during the first deep sleep cycle — the body's natural nocturnal GH pulse. Injecting CJC-1295/Ipamorelin 30–60 minutes before bed amplifies this natural pulse rather than creating an artificial one at an arbitrary time. The result is a larger, more physiological GH release during the deepest, most restorative phase of sleep — which also happens to be when the majority of tissue repair and growth signaling occurs. Users consistently report improved sleep quality within the first week of use, and this isn't a side effect: it's the compound doing exactly what it's supposed to do.
Key Benefits
Dual-receptor GH stimulation produces synergistic GH elevation beyond either compound alone
Ipamorelin component: zero cortisol, prolactin, or ACTH elevation — pure GH selectivity
Significantly improved deep sleep quality within the first week of use
Enhanced fat mobilization and lipolysis across all body fat depots
Improved lean muscle retention and growth via elevated IGF-1
Faster recovery between training sessions — sustains higher training frequency
Improved skin thickness and elasticity as a secondary GH/IGF-1 benefit
Pre-blended 5mg/5mg ratio eliminates the need for two separate compounds
Full Protocol
100mcg CJC-1295 + 100mcg Ipamorelin per injection (from blended vial), 2–3× daily. Best timed: upon waking, pre-workout, and 30–60 min before bed. The bedtime dose leverages the natural GH pulse during sleep. Cycles of 12–16 weeks on, 4–8 weeks off.
